How to cite this software in publications
Other papers describing the software
Papers using CellProfiler and/or CellProfiler Analyst
How to cite this software in publications- the project's survival depends on it!
- CellProfiler for cells:
- Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, Guertin DA, Chang JH, Lindquist RA, Moffat J, Golland P, Sabatini DM (2006) CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biology 7:R100. PMID: 17076895 [link to paper at Genome Biology]
- CellProfiler for other biological images:
- Lamprecht MR, Sabatini DM, Carpenter AE (2007) CellProfiler: free, versatile software for automated biological image analysis. Biotechniques 42(1):71-75. PMID: 17269487 [PDF]
- CellProfiler Analyst software in general:
- Jones TR, Kang IH, Wheeler DB, Lindquist RA, Papallo A, Sabatini DM, Golland P, Carpenter AE (2008) CellProfiler Analyst: data exploration and analysis software for complex image-based screens. BMC Bioinformatics 9(1):482/doi: 10.1186/1471-2105-9-482. PMID: 19014601 PMCID: PMC2614436 [BioMed Central link].
- CellProfiler Analyst for scoring phenotypes by machine learning:
- Jones TR, Carpenter AE, Lamprecht MR, Moffat J, Silver S, Grenier J, Root D, Golland P, Sabatini DM (2009) Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning. PNAS 106(6):1826-1831/doi: 10.1073/pnas.0808843106. PMID: 19188593 PMCID: PMC2634799 [PNAS link]
It's also nice if you cite the website (www.cellprofiler.org) and email us so that we are aware of your publication, but these are much less critical than citing the publications.
Other papers describing the software and/or its methods:
- Overview of process of high-throughput screening with CellProfiler
- Jones TR, Carpenter AE, Golland P, Sabatini DM (2006) Methods for high-content, high-throughput image-based cell screening. Proceedings of the Workshop on Microscopic Image Analysis with Applications in Biology (MIAAB). Metaxas DN, Whitaker RT, Rittcher J, Sebastian T (Eds). Copenhagen, Denmark, October 5, pp 65-72. [PDF]
- Updated as a book chapter:
- Jones TR, Carpenter AE, Golland P, Sabatini DM (2008) Methods for high-content, high throughput image-based cell screening. In: Rittscher J, Machiraju R, Wong STC, eds. Microscopic Image Analysis for Life Science Applications. Norwood, MA: Artech House Publishers; 209-221. (Book chapter)
- Step-by-step CellProfiler tutorial, using human cell cytoplasm-to-nucleus translocation as an example
- Carpenter AE (2007) Extracting rich information from images. In: Clemons PA et al., eds. Cell-Based Assays for High-Throughput Screening, Methods in Molecular Biology 486:14. New York, NY: Humana Press; 193-211. (Book chapter) PMID: 19347625 [PDF]
- Step-by-step CellProfiler tutorial, using yeast colonies as an example
- Vokes, MS and Carpenter, AE (2008) Using CellProfiler for automatic identification and measurement of biological objects in images. In: Ausubel FM et al., eds. Current Protocols in Molecular Biology 82:14.17.1-14.17.12. (Book chapter) PMID: 18425761 [PDF]
- Propagate algorithm in CellProfiler's IdentifySecondary module
- Jones TR, Carpenter AE, Golland P (2005) Voronoi-based segmentation of cells on image manifolds. Proceedings of the ICCV Workshop on Computer Vision for Biomedical Image Applications (CVBIA). Yanxi Liu, Tianzi Jiang, Changshui Zhang (Eds.). Beijing, China, October 21. Lecture Notes in Computer Science 3765. Published by Springer-Verlag, Berlin, p. 535-543, ISBN 3-540-29411-2. [PDF] [poster] [hand traced images]
Papers using CellProfiler and/or CellProfiler Analyst
- Wheeler DB, Bailey SN, Guertin DA, Carpenter AE, Higgins CO, Sabatini DM (2004) RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells. Nature Methods 1(2):1-6. PMID: 15782175 [PDF]
- Bailey SN, Ali SM, Carpenter AE, Higgins CO, Sabatini DM (2006) Microarrays of lentiviruses for gene function screens in immortalized and primary cells. Nature Methods 3(2):117-22. PMID: 16432521 [PDF]
- Baltus AE, Menke DB, Hu YC, Goodheart ML, Carpenter AE, de Rooij DG, Page DC (2006) In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication. Nature Genetics 38(12):1430_1434. PMID: 17115059 [PDF]
- Cowen LE, Carpenter AE, Matangkasombut O, Fink GR, Lindquist S (2006) Genetic architecture of Hsp90-dependent drug resistance. Eukaryotic Cell 5(12):2184-8. PMID: 17056742 [PDF]
- Hartwell KH, Muir B, Reinhardt F, Carpenter AE, Sgroi DC, Weinberg RA (2006) The Spemann Organizer gene, Goosecoid, promotes tumor metastasis. PNAS 103(50):18969-74 PMID: 17142318. [PDF]
- Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE (2006) A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 124(6):1283-98. PMID: 16564017 [PDF]
- Sigal A, Milo M, Cohen A, Geva-Zatorsky N, Klein Y, Alaluf I, Swerdlin N, Perzov N, Danon T, Liron Y, Raveh T, Carpenter AE, Lahav G, Alon U (2006) Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nature Methods 3(7):525-31. PMID 16791210. [PDF]
- Buth H, Buttigieg PL, Ostafe R, Rehders M, Dannenmann SR, Schaschke N, Stark HJ, Boukamp P, Brix K (2007) Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes. European Journal of Cell Biology 86:747-761. PMID: 17651862
- Dai C, Whitesell L, Rogers AB, Lindquist S (2007) Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis. Cell 130:1005-1018. PMID: 17889646
- Kuijl C, Savage NDL, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, van den Nieuwendijk R, van den Eeden SJF, Geluk A, Poot A, van der Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff TH, Neefjes J (2007) Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. Nature 450:725-U710. PMID: 18046412
- Li DD, Shao ZH, Vanden Hoek TL, Brorson JR (2007) Reperfusion accelerates acute neuronal death induced by simulated ischemia. Experimental Neurology 206:280-287. PMID: 17599834
- Lian S, Fritzler MJ, Katz J, Hamazaki T, Terada N, Satoh M, Chan EKL (2007) Small interfering RNA-mediated silencing induces target-dependent assembly of GW/P bodies. Molecular Biology of the Cell 18:3375-3387. PMID: 17596515
- Mu JJ, Wang Y, Luo H, Leng M, Zhang JL, Yang T, Besusso D, Jung SY, Qin J (2007) A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. Journal of Biological Chemistry 282:17330-17334. PMID: 17478428
- Oh TI, Sung JH, Tatosian DA, Shuler ML, Kim D (2007) Real-time fluorescence detection of multiple microscale cell culture analog devices In situ. Cytometry Part A 71A:857-865. PMID: 17559134
- Pincus Z, Theriott JA (2007) Comparison of quantitative methods for cell-shape analysis.Journal of Microscopy-Oxford 227:140-156. PMID: 17845709
- Schlumberger MC, Kappeli R, Wetter M, Muller AJ, Misselwitz B, Dilling S, Kremer M, Hardt WD (2007) Two newly identified SipA domains (F1, F2) steer effector protein localization and contribute to Salmonella host cell manipulation. Molecular Microbiology 65:741-760. PMID: 17635190
- Wiley DJ, Rosqvist R, Schesser K (2007) Induction of the Yersinia type 3 secretion system as an all-or-none phenomenon. Journal of molecular biology 373:27-37. PMID: 17825321
- Bulosan M, Pauley KM, Yo K, Chan EK, Katz J, Peck AB, Cha S (2008) Inflammatory caspases are critical for enhanced cell death in the target tissue of Sjogren's syndrome before disease onset. Immunology and Cell Biology 87(1):81-90. PMID: 18936772
- Chiang S, Bazuine M, Lumeng CN, Geletka LM, Mowers J, White NM, Ma JT, Zhou J, Qi N, Westcott D, Delproposto JB, Blackwell TS, Yull FE, Saltiel AR (2009) The protein kinase IKK[var epsilon] regulates energy balance in obese mice. Cell 138(5):961-975. PMID: 19737522.
- Chariot D, Campa V, Azimi B, Mercola M, Ingermanson R, McDonough PM, Price, JH (2008) Automated calcium measurements in live cardiomyocytes. Fifth IEEE International Symposium on Biomedical Imaging: From Nero to Macro, doi:10.1109/ISBI.2008.4540996.
- Dobbelaere J, Josué F, Suijkerbuijk S, Baum B, Tapon N, Raff J (2008) A Genome-Wide RNAi Screen to Dissect Centriole Duplication and Centrosome Maturation in Drosophila. PLoS Biology 6(9):e224 PMID: 18798690
- Hasegawa Y, Murph M, Yu S, Tigyi G, Mills GB (2008) Lysophosphatidic acid (LPA)-induced vasodilator-stimulated phosphoprotein mediates lamellipodia formation to initiate motility in PC-3 prostate cancer cells. Molecular Oncology 2(1): 54-69. PMID: none
- Liberali P, Ramo P, Pelkmans L (2008) Protein kinases: starting a molecular systems view of endocytosis. Annual Review Pelkmans, L. Annual Review of Cell and Developmental Biology 24:501-523. PMID: 18598215.
- Mayer K, Iolyeva M E, Meyer-Grahle U, Brix K (2008) Intestine-specific expression of green fluorescent protein-tagged cathepsin B: proof-of-principle experiments. Biological Chemistry 389(8):1085-1096. PMID: 18690773
- Pan H, Yu J, Zhang L, Carpenter AE, Zhu, H, Li L, Ma D, Yuan J (2008) A novel small molecule regulator of guanine nucleotide exchange activity of ARF and golgi membrane trafficking. Journal of Biological Chemistry 10.1074/jbc.M806592200. PMID: 18799457
- Sacher R, Stergiou L, Pelkmans L (2008) Lessons from genetics: interpreting complex phenotypes in RNAi screens. Current Opinion in Cell Biology 20(4):483-489. PMID: 18602470.
- Sumiyoshi M, Ricciuto J, Tisdale A, Gipson IK, Mantelli F, Argueso P (2008) Antiadhesive character of mucin O-glycans at the apical surface of corneal epithelial cells. Investigative Ophthalmology & Visual Science 49:197-203. PMID: 18172093
- Tognarini I, Sorace S, Zonefrati R, Galli G, Gozzini A, Carbonell Sala SC, Thyrion GD, Carossino AM, Tanini A, Mavilia C, Azzari C, Sbaiz F, Facchini A, Capanna R, Brandi ML (2008) In vitro differentiation of human mesenchymal stem cells on Ti6Al4V surfaces. Biomaterials 29:809-824. PMID: 18022689
- Handel N, Brockel A, Heindl M, Klein E, Uhlig HH (2009) Cell-cell-neighborhood relations in tissue sections—a quantitative model for tissue cytometry. Cytometry Part A 75(4):356-61. PMID: 19184996
- Ilg K, Endt K, Misselwitz B, Stecher B, Aebi M, Hardt WD (2009) O-antigen-negative Salmonella enterica serovar Typhimurium is attenuated in intestinal colonization but elicits colitis in streptomycin-treated mice. Infection and Immunity 77(6):2568-75 PMID: 19364844. PMCID: PMC2687356.
- Kalany NY, Sabatini DM (2009) Tumours with PI3K activation are resistant to dietary restriction. Nature 458(7239):725-31. PMID: 19279572. PMCID: PMC2692085.
- Lai FPL, Szczodrak M, Oelkers JM, Ladwein M, Acconcia F, Benesch S, Auinger S, Faix J, Small JV, Polo S, Stradal TEB, Rottner K (2009) Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to rho-GTPases. Molecular Biology of the Cell 20(14):3209-3223. PMID: 19458196. PMCID: PMC2710823.
- Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM (2009) High throughput screen for novel antimicrobials using a whole animal infection model. ACS Chemical Biology 4/doi:10.1021/cb900084v. PMID: 19572548
- Ramo P, Sacher R, Snijder B, Begemann B, Pelkmans L (2009) CellClassifier: supervised learning of cellular phenotypes. Bioinformatics 25(22):3028-3030. PMID: 19729371.
- Rocha N, Kuijl C, van der Kant R, Janssen L, Houben D, Janssen H, Zwart W, Neefjes J (2009) Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 glued and late endosome positioning. Journal of Cell Biology 185(7):1209-25. PMID: 19564404. PMCID: PMC2712958.
- Rodier F, Coppé JP, Patil CK, Hoeijmakers WA, Muñoz DP, Raza SR, Freund A, Campeau E, Davalos AR, Campisi J (2009) Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nature Cell Biology 11(8):973-79. PMID: 19597488.
- Snijder B, Sacher R, Ramo P, Damm E, Liberali P, Pelkmans L (2009) Population context determines cell-to-cell variability in endocytosis and virus infection. Nature 461(7263):520-523. PMID: 19710653.
- Tsui M, Xie T, Orth JD, Carpenter AE, Rudnicki S, Kim S, Shamu CE, Mitchison TJ (2009) An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor. PLoS ONE 4(10):e7339. PMID: 19802393. PMCID: PMC2752188.
- Zunder ER, Knight ZA, Houseman BT, Apsel B, Shokat KM T (2009) Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha. Cancer Cell 14(2):180-192. PMID: 18691552. PMCID: PMC2720137.
